Category: Biosynthesis/ acquisition of amino acids
2.3. Amino acid/ nitrogen metabolism
2.3.1. Biosynthesis/ acquisition of amino acids
2.3.1.1. Biosynthesis/ acquisition of glutamate/ glutamine/ ammonium assimilation
Name | Function |
alsT | uptake of glutamine |
glnA | glutamine biosynthesis, control of [protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA] and [protein|641C4BDD9702804642E1753A9C779E80FABB3919|GlnR] activity |
glnH | glutamine uptake |
glnK | regulation of the [gene|1A415DC85354373EA4866733C3AE43F510BD3C56|glsA]-[gene|E371BC4F613C40CB0E8C8CAA97387F3E6735D813|glnT] operon |
glnL | regulation of the glsA-glnT operon |
glnM | glutamine uptake |
glnP | glutamine uptake |
glnQ | glutamine uptake |
glnR | regulation of glutamine synthesis |
glnT | glutamine uptake |
gltA | glutamate biosynthesis |
gltB | glutamate biosynthesis |
gltC | regulation of the glutamate synthase operon ([gene|44DF1B7E476AD58B3CCC39300FFE0132D0D32AD0|gltA]-[gene|AA07CC52B2DD48ACC9D3375E9D531CB1ACBE485A|gltB]) |
gltT | glutamate and aspartate uptake |
nrgA | ammonium uptake |
nrgB | regulation of ammonium uptake |
tnrA | regulation of nitrogen assimilation |
Important reviews
2.3.1.2. Biosynthesis/ acquisition of proline
Name | Function |
proA | biosynthesis of proline |
proB | biosynthesis of proline |
proG | biosynthesis of proline |
proH | osmoadaptive de novo production of proline |
proI | biosynthesis of proline |
proJ | osmoadaptive de novo production of proline |
putP | proline uptake |
2.3.1.3. Biosynthesis/ acquisition of proline/ based on similarity
2.3.1.4. Biosynthesis/ acquisition of arginine
Name | Function |
ahrC | transcriptional regulator of arginine metabolic genes |
argB | biosynthesis of arginine |
argC | biosynthesis of arginine |
argD | biosynthesis of arginine |
argF | biosynthesis of arginine |
argG | biosynthesis of arginine |
argH | biosynthesis of arginine |
argJ | biosynthesis of arginine |
artP | arginine uptake |
artQ | arginine uptake |
artR | arginine uptake |
carA | biosynthesis of arginine |
carB | biosynthesis of arginine |
rocC | arginine, ornithine and citrulline uptake |
rocE | arginine, ornithine and citrulline uptake |
sr1 | control of arginine metabolism and glycolysis |
2.3.1.5. Biosynthesis/ acquisition of aspartate/ asparagine
Name | Function |
asnB | control of peptidoglycan hydrolysis |
asnH | biosynthesis of asparagine |
asnO | biosynthesis of asparagine |
aspB | biosynthesis of aspartate |
yveA | unknown |
2.3.1.6. Biosynthesis/ acquisition of lysine/ threonine
Name | Function |
asd | biosynthesis of threonine, lysine, dipicolic acid, peptidoglycan |
bcaP | uptake of branched-chain amino acids, threonine, and serine |
dapA | biosynthesis of lysine and peptidoglycan |
dapB | biosynthesis of lysine and peptidoglycan |
dapF | biosynthesis of lysine and peptidoglycan |
dapG | biosynthesis of lysine and peptidoglycan |
hom | biosynthesis of methionine and threonine |
lysA | biosynthesis of lysine |
lysC | biosynthesis of lysine |
patA | biosynthesis of lysine and peptidoglycan |
thrB | biosynthesis of threonine |
thrC | biosynthesis of threonine |
thrD | unknown |
thrR | control of threonine biosynthesis |
ybxG | uptake of threonine and serine |
ykuR | biosynthesis of lysine and peptidoglycan |
yvsH | uptake of lysine |
2.3.1.7. Biosynthesis/ acquisition of lysine/ threonine/ based on similarity
Name | Function |
ykuQ | biosynthesis of lysine and peptidoglycan |
2.3.1.8. Biosynthesis/ acquisition of serine/ glycine/ alanine
Name | Function |
aimA | uptake of serine |
bcaP | uptake of branched-chain amino acids, threonine, and serine |
glyA | biosynthesis of glycine |
serA | biosynthesis of serine |
serB | biosynthesis of serine |
serC | biosynthesis of serine |
ybxG | uptake of threonine and serine |
yrbD | uptake of alanine |
2.3.1.9. Biosynthesis/ acquisition of cysteine
Name | Function |
ascR | regulation of sulphur metabolism |
cysE | biosynthesis of cysteine |
cysK | biosynthesis of cysteine, control of [protein|50930C56C27D22715620A350220E3C56ADB41020|CymR] activity |
mccA | methionine-to-cysteine conversion |
mccB | methionine-to-cysteine conversion |
tcyA | cystine uptake |
tcyB | cystine and diaminopimelate uptake |
tcyC | cystine and diaminopimelate uptake |
tcyJ | cystine uptake |
tcyK | cystine uptake |
tcyL | cystine uptake |
tcyM | cystine uptake |
tcyN | cystine uptake |
tcyP | cystine and diaminopimelate uptake |
yxeM | uptake and utilization of S-(2-succino)cysteine |
yxeN | uptake and utilization of S-(2-succino)cysteine |
yxeO | uptake and utilization of S-(2-succino)cysteine |
2.3.1.10. Biosynthesis/ acquisition of methionine/ S-adenosylmethionine
Name | Function |
hom | biosynthesis of methionine and threonine |
luxS | methionine salvage |
metA | biosynthesis of methionine |
metC | biosynthesis of methionine |
metE | biosynthesis of methionine |
metI | biosynthesis of methionine |
metK | S-adenosylmethionine synthesis |
metN | methionine uptake |
metP | methionine uptake |
metQ | methionine uptake |
mtnA | methionine salvage |
mtnB | methionine salvage |
mtnD | methionine salvage |
mtnE | methionine salvage |
mtnK | methionine salvage |
mtnN | methionine salvage |
mtnU | methionine salvage |
mtnW | methionine salvage |
mtnX | methionine salvage |
patB | biosynthesis of methionine |
2.3.1.11. Biosynthesis/ acquisition of methionine/ S-adenosylmethionine/ based on similarity
Name | Function |
ybgG | biosynthesis of methionine |
yitJ | methionine biosynthesis, tetrahydrofolate interconversion |
yoaD | methionine biosynthesis |
yxjG | unknown |
yxjH | unknown |
2.3.1.12. Biosynthesis/ acquisition of branched-chain amino acids
Name | Function |
azlB | regulation of branched-chain amino acid transport |
azlC | export of branched-chain amino acids |
azlD | export of branched-chain amino acids |
bcaP | uptake of branched-chain amino acids, threonine, and serine |
braB | uptake of branched-chain amino acids |
brnQ | uptake of valine and isoleucine |
ilvA | biosynthesis of branched-chain amino acids |
ilvB | biosynthesis of branched-chain amino acids |
ilvC | biosynthesis of branched-chain amino acids |
ilvD | biosynthesis of branched-chain amino acids |
ilvH | biosynthesis of branched-chain amino acids |
leuA | biosynthesis of leucine |
leuB | biosynthesis of leucine |
leuC | biosynthesis of leucine |
leuD | biosynthesis of leucine |
yabJ | deamination of reactive intermediates generated in isoleucine biosynthesis |
ybgE | biosynthesis of branched-chain amino acids |
ywaA | biosynthesis of branched-chain amino acids |
2.3.1.13. Biosynthesis/ acquisition of aromatic amino acids
Name | Function |
aroA | biosynthesis of aromatic amino acids |
aroB | biosynthesis of aromatic amino acids |
aroC | biosynthesis of aromatic amino acids |
aroD | biosynthesis of aromatic amino acids |
aroE | biosynthesis of aromatic amino acids |
aroF | biosynthesis of aromatic amino acids |
aroH | biosynthesis of aromatic amino acids |
aroK | biosynthesis of aromatic amino acids |
hisC | biosynthesis of aromatic amino acids |
mtrB | regulation of tryptophan biosynthesis(and translation) attenuation in the trp operon;repression of the folate operon |
pabA | biosynthesis of folate and tryptophan |
pheA | biosynthesis of phenylalanine |
rtpA | regulation of tryptophan biosynthesis |
trpA | biosynthesis of tryptophan |
trpB | biosynthesis of tryptophan |
trpC | biosynthesis of tryptophan |
trpD | biosynthesis of tryptophan |
trpE | biosynthesis of tryptophan |
trpF | biosynthesis of tryptophan |
trpP | tryptophan uptake |
tyrA | biosynthesis of tyrosine |
2.3.1.14. Biosynthesis/ acquisition of histidine
Name | Function |
hisA | biosynthesis of histidine |
hisB | biosynthesis of histidine |
hisD | biosynthesis of histidine |
hisF | biosynthesis of histidine |
hisG | biosynthesis of histidine |
hisH | biosynthesis of histidine |
hisI | biosynthesis of histidine |
hisJ | biosynthesis of histidine |
hutM | histidine uptake |
prs | phosphoribosylpyrophosphate synthesis (biosynthesis of histidine) |
2.3.1.15. Biosynthesis/acquisition of L- and D-alanine
Name | Function |
alaT | biosynthesis of L-alanine |
alr | peptidoglycan biosynthesis |
dat | peptidoglycan precursor biosynthesis |
ytnA | uptake of D- and L-alanine |
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